Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...
Clascoterone (cortexolone 17α-propionate) is a first-in-class topical anti-androgen approved in 2020 for the treatment of acne in patients aged 12 years and older. It works by blocking androgen ...
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New fusion enzyme boosts recycling of polyester textiles, researchers say
Scientists from the University of Portsmouth and the University of Manchester say they have developed a fusion enzyme that ...
A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...
Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule. The anti-cancer molecule salinosporamide A, also called Marizomb, is in Phase III clinical ...
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A new study finds enhanced activity of a specific enzyme drives spinocerebellar ataxia type 14, which suggests inhibiting the enzyme may have therapeutic potential. pinocerebellar ataxias are a group ...
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