When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits that RNA before it is translated into protein. Many genes can be processed and ...

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

New findings from Karolinska Institutet reveal how the gene HNRNPU coordinates several fundamental molecular processes during ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...

v. 1. Synthesis and purification of RNA substrates / Benoit Chabot -- Characterization of RNA / Paula J. Grabowski -- Splicing of mRNA precursors in mammalian cells / Ian C. Eperon, Adrian R. Krainer ...

A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...

tRNA is an important component of the biological synthesis of new proteins, as it carries a specific amino acid that will be incorporated to the protein through the ribosome machinery, as directed by ...