T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence through multiple pathways, including persistent stimulation by ...

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and other cellular components. Certain elements of the TME can benefit patients ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

Spatial biology is reshaping how researchers study cancer by revealing the architecture and complexity of tumors in extraordinary detail. Through techniques that combine protein- and gene-level ...

Mitochondrial dysfunctions are associated with a variety of pathologies, and the onset and progression of disease are accompanied by alterations in extracellular biochemical and mechanical signals.

Students and Faculty of the Cornell Academic Community are invited to view the webinar. https://weillcornell.zoom.us/meeting/register/tJMldO-uqDIoHd3XQkNVETrvw… The ...

Tea will be served at 12:45 p.m., immediately preceding the seminar. Thursday, November 13, 2025 - 1:00 p.m. to 2:00 p.m.

Stem cells in most organisms typically take cues from adjacent cells. But new research from the Stowers Institute for Medical Research reveals planarian stem cells ignore their nearest neighbors and ...