For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

Using a tool to solve a protein's structure, for most researchers in the world of structural biology and computational ...

The protein 'MIPS' changes its internal structure when it becomes active. Its disordered active centre becomes a defined structure with special functions. The protein plays a key role in the ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

Researchers combined AI simulations with NMR data to capture fleeting structures of intrinsically disordered proteins, offering new insight into protein misfolding linked to neurodegenerative diseases ...

Researchers have revealed how bacteria precisely control the genes that trigger cell division. The study shows that the MraZ protein, which normally forms a donut-shaped structure, must bend and ...

Advanced proteomics and AI reveal blood protein changes, offering insights into early Alzheimer's detection and differentiation from mild cognitive impairment.

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...